Rannou Fabrice

Activités de recherche

Drouet A, Zagnoli F, Fassier T, Rannou F, Baverel F, Piraud M, Bahuau M, Petit F, Streichenberger N, Marcorelles P, and Vital Durand D (2013). Exercise-induced muscle pain due to phosphofrutokinase deficiency: Diagnostic contribution of metabolic explorations (exercise tests, 31P-nuclear magnetic resonance spectroscopy). Rev Neurol (Paris) 169: 613-624.

Gueret G, Guillouet M, Vermeersch V, Guillard E, Talarmin H, Nguyen BV, Rannou F, Giroux-Metges MA, Pennec JP, Ozier Y (2013). La neuromyopathie acquise en réanimation. Ann Fr Anesth Reanim 32, 580-591.

Guillouet M, Rannou F, Giroux-Metges MA, Droguet M, Pennec JP (2013). Tumor necrosis factor alpha induced hypoexciability in rat muscle evidenced in a model of ion currents and action potential.
Cytokine 64(1), 165-171.

Guillard E, Gueret G, Guillouet M, Vermeesch V, Rannou F, Giroux-Metges MA, Pennec JP (2013). Alteration of muscle membrane excitability in sepsis: Possible involvement of ciliary nervous trophic factor (CNTF). Cytokine 63, 52-57.

Rannou F, Leschiera R, Giroux-Metges MA, Pennec JP (2012). Effects of lactate on the voltage- gated sodium channels of rat skeletal muscle: modulating current opinion. J Appl Physiol 112, 1454-1455.

Guillouet M, Gueret G, Rannou F, Giroux-Metges MA, Gioux M, Arvieux CC, Pennec JP (2011). Tumor necrosis factor-alpha down regulates sodium current in skeletal muscle by protein kinase C activation: involvement in critical illness polyneuromyopathy. AJP Cell Physiol 301, C1057-1063.

Rannou F, Pennec JP, Morel J, Guéret G, Leschiera R, Droguet M, Gioux M, Giroux-Metges MA (2011). Nav 1.4 and Nav 1.5 are
modulated differently during muscle immobilization. J Appl Physiol 111, 495-507.

Guillouet M, Gueret G, Rannou F, Giroux-Metges MA, Gioux M, Arvieux CC, Pennec P (2011). TNFa increases resting potential in isolated fibres from rat Peroneus longus by a PKC mediated mechanism: involvement in ICU acquired polyneuromyopathy. Cytokine 56, 149-152.

Morel J, Rannou F, Talarmin H, Giroux-Metges MA, Pennec JP, Dorange G, Gueret G (2010). Sodium channel NaV1.5 expression is enhanced in cultured adult rat skeletal muscle fibres. J of membrane Biology 235 109-119.

Pennec JP, Guillouet M, Rannou F, Arvieux CC & Gueret G (2010). Hemodynamic effects of lipid emulsion after local anesthetic intoxication may be due to a direct effect of fatty acids on myocardial voltage-dependent calcium channels. Can J Anaesth 57, 947.

Rannou F, Droguet M, Giroux-Metges MA, Pennec Y, Gioux M, Pennec JP (2009). Differences in sodium voltage-gated channel properties according to myosin heavy chain isoforms expression in
single muscle fibre. J Physiol (London) 587, 5249-5258.

Rossignol B, Gueret G, Pennec JP, Morel J, Rannou F,
Giroux-Metges MA, Talarmin H, Gioux M, Arvieux CC (2008). Effects of chronic sepsis on contractile properties of fast twitch muscle in an experimental model of critical illness neuromyopathy in the rat. Crit Care Med 36, 1855-1863.

Rannou F, Pennec JP, Rossignol B, Morel J, Dorange G, Arvieux C, Gioux M, Giroux-Metges MA (2007). Effects of chronic sepsis on rat motor units: experimental study of critical illness polyneuromyopathy. Exp Neurol 204, 741-747.

Projets de recherche

- Effects of immobilization on the contractile phenotype and excitability of skeletal muscle.

- Metabolic myopathies: evaluation by exercise testing.